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. 2014 Feb 1;25(3):380–396. doi: 10.1091/mbc.E13-07-0363

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© 2014 Georgess et al. This article is distributed by The American Society for Cell Biology under license from the author(s). Two months after publication it is available to the public under an Attribution–Noncommercial–Share Alike 3.0 Unported Creative Commons License (http://creativecommons.org/licenses/by-nc-sa/3.0).

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FIGURE 8: — RhoE^gt/gt OCs show impaired migration. (A) Top, micrographs of time-lapse imaging showing Sp-OC migration tracks (red). Scale bar, 40 μm. Bottom, representative rose plots of 5 RhoE^+/+ and 5 RhoE^gt/gt OC migration tracks for a total duration of 8 h/track. (B) Plots of migration parameters of migrating OCs (RhoE^+/+, n = 84 tracks, 1870 time points; RhoE^gt/gt, n = 39 tracks, 1214 time points). Left, instantaneous velocity of displacement (i.e., speed between two consecutive positions). Middle, instantaneous persistence of OC migration (P_i = d_i/D_i). Right, frequency distribution of angle change between two consecutive movements. Raw values are represented with dots and fitted with a Gaussian function. Error bars are SEM.