Table 1. PTBP1 repressed exons identified by the splicing model.
| Gene Name | Gene Description | mm9 coordinates | PTB Binding Scores | 3′ | p(Repressed) | ||
| Upstream | Downstream | Splice site | |||||
| Intron (250 nt) | Exon | Intron (100 nt) | Strength | ||||
| Pax6 | paired box gene 6 | chr2:105523985–105524115(+) | 8.35 | −1.49 | −0.80 | 0.27 | 0.99 |
| Mbd5 | methyl-CpG binding domain protein 5 | chr2:49134101–49135303(+) | 6.46 | −0.93 | 2.27 | −0.32 | 0.98 |
| Arhgap24 | Rho GTPase activating protein 24 | chr5:102981145–102981338(+) | 6.47 | 0.10 | −0.05 | 0.46 | 0.97 |
| Tle1 | transducin-like enhancer of split 1 | chr4:71819247–71819451(−) | 4.71 | 0.05 | −1.26 | −2.56 | 0.94 |
| Acsl6 | acyl-CoA synthetase long-chain family | chr11:54150438–54150515(+) | 4.16 | 1.40 | −0.03 | −0.82 | 0.94 |
| Ryr1 | ryanodine receptor 1, skeletal muscle | chr7:29829938–29829955(−) | 4.78 | −0.08 | −0.88 | −1.71 | 0.94 |
| Ankhd1 | ankyrin repeat and KH domain containing 1 | chr18:36784163–36784921(+) | 4.37 | 0.03 | 1.44 | −0.64 | 0.93 |
| Slc39a14 | solute carrier family 39 (zinc transporter) | chr14:70713408–70713577(−) | 3.51 | 1.16 | −1.27 | −3.20 | 0.92 |
| Gabrg2 | gamma-aminobutyric acid (GABA) A receptor | chr11:41727472–41727495(−) | 1.95 | 2.77 | 0.56 | −3.79 | 0.92 |
| Itga7 | integrin alpha 7 | chr10:128378878–128378997(+) | 4.14 | 0.29 | 1.13 | −0.25 | 0.92 |
| Iqsec2 | IQ motif and Sec7 domain 2 | chrX:148615540–148615635(+) | 4.88 | 0.68 | −0.13 | 0.71 | 0.91 |
| Smarca2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin | chr19:26825612–26825646(+) | 3.94 | −0.09 | 1.23 | −0.86 | 0.91 |
| Zfand3 | zinc finger, AN1-type domain 3 | chr17:30197755–30197795(+) | 4.17 | 2.34 | 0.90 | 1.80 | 0.91 |
| Agap2 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 | chr10:126527198–126527257(+) | 3.57 | 0.06 | −0.53 | −3.08 | 0.90 |
| Ttn | Titin | chr2:76723554–76723832(−) | 2.93 | 1.06 | 1.19 | −1.83 | 0.90 |
| Ptbp3 | ROD1 regulator of differentiation 1 (S. pombe) | chr4:59559021–59559054(−) | 3.80 | 0.57 | 1.66 | 0.73 | 0.89 |
| Mapk8 | mitogen-activated protein kinase 8 | chr14:34203859–34203930(−) | 2.35 | 1.17 | 1.01 | −3.48 | 0.89 |
| Snap91 | synaptosomal-associated protein 91 | chr9:86693373–86693534(−) | 2.60 | 1.89 | −0.35 | −2.17 | 0.88 |
| Fmnl1 | formin-like 1 | chr11:103059449–103059547(+) | 3.93 | −0.60 | −1.36 | −2.70 | 0.88 |
| Phldb1 | pleckstrin homology-like domain, family B | chr9:44509029–44509169(−) | 3.20 | 0.57 | 1.05 | −0.66 | 0.87 |
| 2310035C23Rik | RIKEN cDNA 2310035C23 gene | chr1:107637012–107637094(+) | 2.03 | 1.76 | 0.85 | −2.46 | 0.87 |
| Arnt | aryl hydrocarbon receptor nuclear translocator | chr3:95270715–95270759(+) | 3.48 | −0.36 | 2.53 | 0.09 | 0.87 |
| Smyd2 | SET and MYND domain containing 2 | chr1:191723697–191723807(−) | 3.33 | 0.33 | −0.28 | −1.64 | 0.86 |
| Ap2a1 | adaptor protein complex AP-2, alpha 1 subunit | chr7:52158832–52158897(−) | 3.35 | −0.12 | −0.89 | −2.69 | 0.86 |
| Klra | killer cell lectin-like receptor, subfamily A | chr6:130329011–130329100(−) | 2.82 | 3.18 | 0.62 | 0.77 | 0.86 |
| Spag9 | sperm associated antigen 9 | chr11: 93942054–93942068(+) | 0.99 | 3.01 | 1.62 | −3.03 | 0.86 |
| Col4a3bp | collagen, type IV, alpha 3 binding protein | chr13:97386949–97387026(+) | 2.81 | 1.23 | 0.74 | −0.93 | 0.86 |
| Garnl3 | GTPase activating RANGAP domain-like 3 | chr2:32941395–32941464(−) | 4.15 | 0.38 | 0.36 | 0.94 | 0.86 |
| Dennd1a | DENN/MADD domain containing 1A | chr2:37982049–37982168(−) | 3.37 | 0.80 | 1.35 | 0.59 | 0.86 |
| Ms4a7 | membrane-spanning 4-domains, subfamily A | chr19:11400297–11400353(−) | 2.79 | 2.35 | 0.37 | −0.05 | 0.86 |
| BC030307 | cDNA sequence BC030307 | chr10:86169981–86170089(+) | 2.75 | −0.16 | 1.95 | −2.40 | 0.85 |
| Phactr1 | phosphatase and actin regulator 1 | chr13:43154940–43155146(+) | 2.73 | 1.25 | 0.50 | −0.97 | 0.85 |
| R3hdm2 | R3H domain containing 2 | chr10:126902187–126902240(+) | 1.66 | 1.98 | 1.96 | −1.57 | 0.84 |
| Cdc14b | CDC14 cell division cycle 14B | chr13:64306579–64306725(−) | 1.42 | 2.75 | 2.44 | −0.58 | 0.84 |
| Ubqln1 | ubiquilin 1 | chr13:58282183–58282266(−) | 2.88 | 0.98 | −0.06 | −1.17 | 0.84 |
| Ttn | Titin | chr2:76739898–76740179(−) | 2.63 | −0.07 | 1.49 | −2.38 | 0.84 |
| Stx3 | syntaxin 3 | chr19:11857290–11857400(−) | 3.00 | −1.12 | 2.26 | −3.62 | 0.84 |
| Slc8a3 | solute (sodium/calcium) carrier family 8 | chr12: 82310340–82310458(−) | 1.84 | 1.25 | 1.76 | −2.25 | 0.84 |
| Zfp62 | zinc finger protein 62 | chr11:49028057–49028156(+) | 3.27 | 1.98 | −0.51 | 0.19 | 0.83 |
| Dlg1 | discs, large homolog 1 (Drosophila) | chr16:31771843–31771941(+) | 1.53 | 1.98 | 1.87 | −1.65 | 0.83 |
| Nrxn2 | neurexin II | chr19:6463824–6463847(+) | 3.35 | −1.37 | 1.33 | −2.26 | 0.83 |
| Klra7 | killer cell lectin-like receptor, subfamily A | chr6:130179953–130180042(−) | 2.68 | 2.11 | −0.39 | −0.63 | 0.83 |
| Picalm | phosphatidylinositol binding clathrin assembly | chr7:97330729–97330878(+) | 1.15 | 2.15 | 2.30 | −2.37 | 0.83 |
| Acad8 | acyl-Coenzyme A dehydrogenase family | chr9:26798168–26798277(−) | 2.61 | 0.88 | −0.31 | −1.86 | 0.83 |
| Epn1 | epsin 1 | chr7:5033620–5033723(+) | 3.92 | 0.65 | 0.07 | 1.06 | 0.82 |
| Grip1 | glutamate receptor interacting protein 1 | chr10:119422530–119422685(+) | 2.66 | −0.74 | 2.61 | −3.13 | 0.82 |
| Csmd3 | CUB and Sushi multiple domains 3 | chr15:47587514–47587627(−) | 2.42 | 2.16 | 0.20 | −0.45 | 0.82 |
| Lrrfip1 | leucine rich repeat (in FLII) interacting protein 1 | chr1:92990137–92990214(+) | 2.02 | 0.40 | 3.44 | −2.21 | 0.82 |
| Srsf11 | serine/arginine-rich splicing factor 11 | chr3:157703405–157703586(+) | 1.09 | 2.05 | −0.56 | −4.75 | 0.82 |
| Tmem209 | transmembrane protein 209 | chr6:30441087–30441184(−) | 3.82 | 0.16 | 0.10 | 0.64 | 0.82 |
The 50 highest scoring exons predicted to be repressed by PTBP1 based on sequence alone.