Table 4. Rare and common variants contribute to the association signal to HDL-C in gene CETP.
Variant | MAF | MAC | Allele | Type | Beta | P-value1 |
rs3764261 | .27 | 3913 | A | array SNP | 0.28 | 1.6E-40 |
rs5883 | .040 | 490 | T | coding-synonymous | 0.22 | 5.2E-06 |
rs5880 | .024 | 296 | C | missense probably damaging | −0.29 | 4.2E-05 |
rs2303790 | .00057 | 7 | G | missense possibly damaging | 1.31 | 1.0E-03 |
P-values for rs3764261 and rs5880 may be different from those recorded in Table 2 because of the addition of rs2303790 and rs5883 to the model. MAC: minor allele count.