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. 2014 Jan 30;9(1):e86843. doi: 10.1371/journal.pone.0086843

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© 2014 Megison et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

PMC Copyright notice

Formalin-fixed, paraffin embedded samples of SK-NEP-1 tumor xenografts (those presented in the data in Figure 5) were stained for HSV using immunohistochemistry, and representative photomicrographs presented. A No HSV was detected by immunohistochemical staining in SK-NEP-1 tumors treated with vehicle alone. Negative controls (rabbit IgG) were included with each run (small box insert). B HSV immunohistochemical staining revealed HSV present in the M002 treated SK-NEP-1 xenografts (brown stain). There was no viral staining seen in the negative controls (rabbit IgG) (small box insert).