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. 2014 Jan 30;9(1):e87787. doi: 10.1371/journal.pone.0087787

Figure 1. PBA treatment inhibited ER stress and ameliorated atherosclerosis in vivo.

Figure 1

A. Protein was obtained from the thoracic and abdominal aorta of ApoE−/− mice with or without PBA treatment and the expressions of phosphorylated eIF-2α (p-eIF2α), total eIF-2α, spliced XBP-1 (sXBP-1) and β-actin were detected by Western Blot. (n = 2 per group) B. The aortic root sections were stained by rabbit anti- phosphorylated-PERK (p-PERK) and expression of p-PERK in plaque was analyzed by immunohistochemistry. (n = 10 per group), *p<0.05, ***p<0.001.