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. 2014 Jan 30;9(1):e87212. doi: 10.1371/journal.pone.0087212

Figure 4. Analysis of germline/somatic aberrations on chromosome 14q24 of breast cancer cell line CRL-2324.

Figure 4

Breast cancer cell line CRL-2324 and matched normal cell line CRL-2325 are analyzed by GIANT, and results on chromosome 14q24 are provided for demonstrating the performance in identifying the germline/somatic aberration. (a) Results of matched normal cell line CRL-2325 showing germline (green) LOH on this region. (b) Results of breast cancer cell line CRL-2324 showing this germline LOH is flanked by somatic (red) LOH. (c) Consistent results observed in dilution sample with 50% cancer cells. (d) Results of OncoSNP for the same dilution sample.