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. 2014 Jan 30;9(1):e87848. doi: 10.1371/journal.pone.0087848

Figure 1. KDT501 agonistic effect on PPAR reporter activity.

Figure 1

PPARα reporter cells were treated with various concentrations of GW590735 (round circles), rosiglitazone (black triangles) and KDT501 (black squares) (A). PPARγ reporter cells were treated with various concentrations of rosiglitazone, telmisartan (white squares), and KDT501 (B). PPARδ reporter cells were treated with GW0742 (white triangles), rosiglitazone and KDT501(C). Cells were treated for 20 hr and relative luminescence units (RLU) were measured as described in the methods. Agonist concentrations were transformed to log10 µM. Agonist dose- responses were plotted by non-linear regression. Data represent Mean± SD.