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. 2011 Sep 2;51(2):233–244. doi: 10.1007/s13197-011-0500-3

Table 4.

Concentrations of nisin, Pediocin 34 and Enterocin FH99 used alone and in different combinations to evaluate cell growth inhibition by bacteriocins

ADDITIVEa SYNERGISTICb
Pathogen N+P N+E E+P N+P+E N+P N+E E+P N+P+E
Listeria monocytogenes MTCC 657 50 + 600 50 + 700 600 + 700 50 + 600 + 700 25 + 300 25 + 350 300 + 350 25 + 300 + 350
E. faecium DSMZ 20477 53.5 + 70 53.5 + 937.5 937.5 + 70 53.5 + 70 + 937.5 26.25 + 35 26.25 + 468.75 468.75 + 35 26.25 + 35 + 468.75
E. faecium VRE 14 + 2187.5 14 + 3750 2187.5 + 3750 14 + 2187.5 + 3750 7 + 1093 7 + 1875 1093 + 1875 7 + 1093 + 1875

N Nisin, P Pediocin 34, E Enterocin FH99

Units for concentrations: Nisin = IU/ml, Pediocin 34 = AU/ml, Enterocin FH99 = AU/ml

aCombination of bacteriocins corresponded to MICs of the target organisms

bCombination of bacteriocins correspond to Half the concentration of MICs of target organisms