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. 2014 Jan 31;8:23. doi: 10.3389/fncel.2014.00023

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Copyright © 2014 Martin and Manzoni.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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LTD is normal in VPA exposed mPFC neurons. (A) Time course of normalized fEPSP responses from layer V/VI adult rats treated with saline or VPA in utero. 10 Hz eCB-LTD stimulation is indicated by bar. (B) Change in normalized fEPSP pre- (Baseline) and post- (LTD; 25 min after 10 Hz stimulation) eCB-LTD. Darker points represent the mean fEPSP. (C) Cumulative probability plot of percent LTD from individual experiments. Data shown as mean ± s.e.m.; * p < 0.05, ** p < 0.01.