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. 2014 Jan 21;4:153–161. doi: 10.1016/j.fob.2014.01.007

Table 2.

Antiproliferative activity of WT1-pTj on WT1-expressing tumor cell lines and nontumor forming cell lines.

Cell lines EC50a (mol/l x 10−3)
A2058 human melanoma 0.455 ± 0.032
SK-MEL-28 human melanoma 0.680 ± 0.020
B16F10-Nex2 murine melanoma 0.466 ± 0.067
MCF-7 human breast cancer 0.247 ± 0.058
MDA-MB231 human breast cancer 0.759 ± 1.40
OVCAR-3 human ovarian cancer 0.208 ± 0.02
HL-60 human acute leukemia >1
HFF human foreskin fibroblast >1
MEF murine embryonic fibroblast >1
a

EC50 is the concentration that decreases viability by 50% in a dose-dependent survival curve.