Table 1.
The effect of each group on DAI, colon length and histopathological score in DSS-induced acute experimental colitis.
Group | DAI | Colon length | Histopathological score |
---|---|---|---|
Control | 0.12 ± 0.5 bc | 19.09 ± 0.41 bc | 0 bc |
DSS | 7.75 ± 0.75 ac | 15.62 ± 0.39 ac | 8.50 ± 0.93 ac |
DSS + normal saline | 7.12 ± 0.64 ac | 15.59 ± 0.41 ac | 8.75 ± 0.71 ac |
Mesalazine | 6.00 ± 0.93 ab | 17.38 ± 0.47 ab | 6.38 ± 0.74 ab |
VSL#3 | 6.25 ± 0.71 ab | 17.05 ± 0.33 ab | 6.50 ± 0.76 ab |
Heat-killed VSL#3 | 6.12 ± 0.84 ab | 16.95 ± 0.47 ab | 6.38 ± 0.52 ab |
Mesalazine + VSL#3 | 5.00 ± 0.76 abc | 18.05 ± 0.58 abc | 4.88 ± 0.84 abc |
p < 0.05 compared with the control group;
p < 0.05 compared with the model group;
p < 0.05 compared with the mesalazine group.