Table 1.

Epirubicin (Epi) in Pluronic (Plu)/polyacrylic acid (PAA) hydrogels of both liquid and solid suppository formulations.

Hydrogel formulations	Composition (wt %)
Formulation 1	Plu 14%/PAA 0.75%/Epi 50 μg/mL	Liquid suppository
Formulation 2	Plu 14%/PAA 0.375%/Epi 50 μg/mL
Formulation 3	Plu 14%/PAA 0.1875%/Epi 50 μg/mL
Formulation 4	Cocoa butter 0.5 g/Plu 14%/PAA 0.75%/Epi 50 μg/mL	Solid suppository
Formulation 5	Cocoa butter 0.5 g/Plu 14%/PAA 0.375%/Epi 50 μg/mL
Formulation 6	Cocoa butter 0.5 g/Plu 14%/PAA 0.1875%/Epi 50 μg/mL