Table 5.

Brief introduction of the softwares and websites.

Function	Software and website
To search nucleotide sequence	http://www.ncbi.nlm.nih.gov/nuccore/ [29]
To find conserved sequence	MEGA 5.1/DNAstar/DNAMAN [30]
To design primers in the conserved sequence	Oligo 7.0/Primer Premier 5 [31,32]
To find open reading frame	http://www.ncbi.nlm.nih.gov/gorf/gorf.html [33]
To analysis amino sequence	PROTEAN program/DNAMAN [17,30]
To analysis identity of amino acid	http://blast.ncbi.nlm.nih.gov/Blast.cgi [34]
To alignmultiple sequence	MAFFT Multiple program/Sequence Alignment [18]
To analysis phylogenetic	MAFFT Multiple program/Sequence Alignment/MEGA 5.1 [18]
To predict secondary structure	Bioinformatics Toolkit Quick2D program [35]
To predict 3D structure	http://swissmodel.expasy.org/ [20]
To analysis 3D structure	Swiss-PDB Viewer program [20]
To predict antigenic properties	http://imed.med.ucm.es/Tools/antigenic.pl [36]