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IL-6 and IL-6R interaction promotes cell migration and ICAM-1 expression. (A–C) Cells were pretreated with IL-6R monoclonal antibody (mAb) (10 μg/mL) for 30 min followed by stimulation with IL-6 (30 ng/mL) for 24 h. The in vitro migration activity and ICAM-1 expression were measured with the Transwell, wound healing, and qPCR assays (n = 5); *, p < 0.05 compared with the control; #, p < 0.05 compared with the IL-6-treated group.
