Table 2.
Comparison of the release parameters of the nanofibers (n = 6).
| Nanofiber No. | Release in the 1st phase (1 min) | Release after 24 h b | Release in the 2nd phase | ||
|---|---|---|---|---|---|
|
|
|
||||
| Theoretical a | Experimental b | Theoretical a | Experimental b | ||
| F1 | - | 10.7% (2.1) | 85.4% (17.1) | - | 74.7% (14.9) |
| F3 | 33.3% (6.7) | 41.6% (8.3) | 92.7% (18.5) | 66.7% (13.3) | 51.1% (10.2) |
| F4 | 20.0% (4.0) | 28.7% (5.7) | 91.4% (18.3) | 80.0% (16.0) | 62.7% (12.5) |
a
Calculated according to the equation: P = (Fs × Cs)/[(Fs × Cs) + (Fc × Cc)]. Fs, Fc, Cs and Cc represent the flow rates and drug contents of the sheath and core fluids, respectively;
b
Expressed as mean values and the numbers in the brackets represents the absolute drug release amount in mg.