Table 1.

Clinical and laboratory characteristics of the three patients.

Patient number and sex (M/F)	Birth weight and gestational age	Head circumference	Insulin levels N = 5–25	C-peptide levels N = 298–1324	Age at death
ISR1 – F	1700 g (−2.2 SD); 36 weeks	32.5 cm (−2 SD) at 14 days	3560 IU/mL (age: 1 month)	15900 pmol/L (age: 1 month)	18 months
ISR2 – M	1540 g (−2 SD); 34 weeks	31 cm (−3 SD) at birth	4500 IU/mL (at birth)	Not available	40 days
ISR3 – M	1770 g (−2.5 SD); 38 weeks	32.6 cm (−2 SD) at birth	2761, 4300, 21525 IU/mL (at birth)	24825 pmol/L	12 months

N, normal.