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cGMP levels in the cerebral microvessels and brains of wild type and eNOS-/- mice treated with nitroglycerine or vehicle. cGMP was measured via immunoassay in the cerebral microvessel of (A) wild type and (B) eNOS-/- mice. cGMP measured in the brain tissue of (C) wild type and (D) eNOS-/- animals. Data is presented as mean ± SD (n=6-7, P<0.01).
