Table 2.

Mean (±standard deviation) probing pocket depth (PPD) outcome measures at baseline and 12 weeks

Variable	Time point	Treatment group				p-value
		SRP		SRP + P		For mean	For delta
		Mean ± SD	Delta ± SD	Mean ± SD	Delta ± SD
PPD (mm)
Overall	Baseline	4.32 ± 0.50		4.15 ± 0.71		NS
	12 weeks	2.93 ± 0.40*	−1.39 ± 0.15	2.73 ± 0.57*	−1.41 ± 0.25	0.097	NS
Moderate pockets	Baseline	4.84 ± 0.12		4.77 ± 0.24		NS
	12 weeks	3.12 ± 0.22*	−1.72 ± 0.17	2.94 ± 0.40*	−1.84 ± 0.22	0.055	0.041
Deep pockets	Baseline	7.21 ± 0.25		7.27 ± 0.57		NS
	12 weeks	4.95 ± 0.41*	−2.25 ± 0.27	4.39 ± 0.48*	−2.88 ± 0.35	<0.001	<0.001
% Sites with PPD
≥5 mm	Baseline	44.85% ± 13.52		40.21% ± 19.81		NS
	12 weeks	10.89% ± 7.40*		5.92% ± 11.83*		0.004
≥6 mm	Baseline	19.84% ± 11.79		15.88% ± 15.03		NS
	12 weeks	4.05% ± 3.93*		2.89% ± 6.32*		0.064
≥7 mm	Baseline	10.69% ±7.48		9.69% ±12.71		NS
	12 weeks	0.82% ± 1.38*		0.51% ± 1.61*		NS
% Teeth with PPD
≥5 mm	Baseline	87.31% ± 11.31		81.16% ± 19.07		NS
	12 weeks	34.87% ± 19.33*		17.08% ± 23.74*		0.004
≥6 mm	Baseline	54.71% ± 23.99		44.58% ± 26.76		NS
	12 weeks	16.05% ± 14.44*		11.06% ± 19.53*		0.081
≥7 mm	Baseline	36.18% ± 21.35		29.50% ± 24.75		NS
	12 weeks	3.44% ± 5.48*		2.22% ± 6.46*		NS
Number of patients with PPD
≥5 mm	Baseline	15		15		NS
	12 weeks	15		11		NS
≥6 mm	Baseline	15		15		NS
	12 weeks	13		9*		NS
≥7 mm	Baseline	15		15		NS
	12 weeks	6*		3*		NS
Number of patients according to risk for disease progression (Lang & Tonetti 2003)
Low		2/15 (13.3%)		9/15 (60.0%)		0.027
Medium		3/15 (20.0%)		2/15 (13.3%)
High		10/15 (66.6%)		4/15 (26.6%)

Significance of differences between groups: p > 0.1: not significant (NS); p < 0.1 to > 0.05: tendency; p < 0.05: significant (bold).

^*Significantly different from baseline.

SRP, scaling and rootplaning + placebo lozenge; SRP + P, scaling and rootplaning + probiotic lozenge.