Table 3.

Mean (±standard deviation) CAL, REC, BOP and need for surgery outcome measures at baseline and 12 weeks

Variable	Time point	Treatment group				p-value
		SRP		SRP + P
		Mean ± SD	Delta ± SD	Mean ± SD	Delta ± SD	For mean	For delta
CAL (mm)
Overall	Baseline	4.97 ± 0.61		4.97 ± 1.01		NS
	12 weeks	4.21 ± 0.67*	−0.76 ± 0.36	3.97 ± 0.97	−0.99 ± 0.22	NS	0.074
Moderate pockets	Baseline	5.49 ± 0.31		5.60 ± 0.60*		NS
	12 weeks	4.48 ± 0.55*	−1.01 ± 0.59	4.18 ± 0.70	−1.42 ± 0.27	NS	0.014
Deep pockets	Baseline	7.77 ± 0.43		8.19 ± 1.34		NS
	12 weeks	7.10 ± 0.78*	−0.68 ± 0.85	6.72 ± 1.06*	−1.47 ± 0.71	NS	0.007
REC (mm)
Overall	Baseline	0.66 ± 0.73		0.82 ± 0.71		NS
	12 weeks	1.28 ± 0.42*	0.63 ± 0.31	1.24 ± 0.75*	0.42 ± 0.18	NS	0.089
BOP (%)
Overall	Baseline	67.53% ± 11.37		70.70% ± 14.53		NS
	12 weeks	16.58% ± 10.54*		15.51% ± 11.92*		NS
% Sites in need for surgery
Overall	Baseline	41.17% ± 12.2		38.42% ± 30.33		NS
	12 weeks	6.44% ± 5.45*		5.03% ± 9.92*		0.081
Moderate pockets	Baseline	59.80% ± 5.77		60.88% ± 20.17		NS
	12 weeks	3.81% ± 3.31*		2.96% ± 4.76*		NS
Deep pockets	Baseline	100% ± 0		100% ± 0		NS
	12 weeks	34.43% ± 21.30*		18.30% ± 23.00*		0.045
% Teeth in need for surgery
Overall	Baseline	82.27% ± 14.36		78.58% ± 20.02		NS
	12 weeks	25.17% ± 18.38*		15.74% ± 23.34*		0.067
Number of patients in need for surgery
0 sites		2/15 (13.3%)		5/15 (33.3%)		0.019
1-2 sites		0/15 (0%)		4/15 (26.6%)
≥ 3 sites		13/15 (86.6%)		6/15 (40.0%)

Significance of differences between groups: p > 0.1: not significant (NS); p < 0.1 to > 0.05: tendency; p < 0.05: significant (bold).

^*Significantly different from baseline.

SRP, scaling and rootplaning + placebo lozenge; SRP + P, scaling and rootplaning + probiotic lozenge; REC, gingival recession, BOP, bleeding on probing.