Table 5.
Species | Time point | Mean log10 cfu/ml ± SD | Δ mean log10 cfu/ml | ||||
---|---|---|---|---|---|---|---|
SRP | SRP + P | p-value | SRP | SRP + P | p-value | ||
Aggregatibacter actinomycetemcomitans | Baseline | 3.57 ± 1.97 | 3.84 ± 2.7 | NS | |||
3 weeks | 0.69 ± 1.83* | 0.63 ± 1.76* | NS | −3.32 ± 1.03 | −4.38 ± 1.78 | NS | |
6 weeks | 0.77 ± 2.05* | 0.97 ± 2.15* | NS | −3.22 ± 1.18 | −3.92 ± 2.08 | NS | |
9 weeks | 0.96 ± 2.12* | 1.19 ± 2.38* | NS | −3.01 ± 1.25 | −3.61 ± 2.19 | NS | |
12 weeks | 1.86 ± 2.12* | 1.98 ± 2.38* | NS | −1.98 ± 1.23 | −2.53 ± 1.98 | NS | |
Fusobacterium nucleatum | Baseline | 7.4 ± 1.16 | 7.7 ± 1.11 | NS | |||
3 weeks | 2.94 ± 2.25* | 2.95 ± 1.82* | NS | −4.46 ± 2.15 | −4.75 ± 2.37 | NS | |
6 weeks | 3.71 ± 2.09* | 4.38 ± 2.22* | NS | −3,69 ± 2.07 | −3.32 ± 2.39 | NS | |
9 weeks | 4.92 ± 1.39* | 4.6 ± 2.03* | NS | −2.47 ± 1.61 | −3.1 ± 2.22 | NS | |
12 weeks | 5.87 ± 1.08* | 5.45 ± 2.05* | NS | −1.53 ± 1.31 | −2.25 ± 1.89 | NS | |
Porphyromonas gingivalis | Baseline | 6.37 ± 1.7 | 6.67 ± 1.5 | NS | |||
3 weeks | 3.26 ± 1.47* | 3.17 ± 1.71* | NS | −3.11 ± 1.54 | −3.5 ± 1.48 | NS | |
6 weeks | 4.08 ± 1.61* | 3.89 ± 1.23* | NS | −2.3 ± 1.37 | −2.79 ± 1.31 | NS | |
9 weeks | 4.98 ± 1.5* | 4.23 ± 1.23* | NS | −1.39 ± 0.79 | −2.44 ± 1.43 | 0.034 | |
12 weeks | 5.43 ± 1.73* | 4.87 ± 1.21* | NS | −0.94 ± 0.61 | −1.8 ± 1.17 | 0.050 | |
Prevotella intermedia | Baseline | 6.17 ± 2.73 | 6.34 ± 2.14 | NS | |||
3 weeks | 2.47 ± 1.7* | 2.22 ± 2.02* | NS | −4,27 ± 1.79 | −4.12 ± 1.88 | NS | |
6 weeks | 3.55 ± 1.75* | 2.7 ± 2.06* | NS | −3.02 ± 1.21 | −3.63 ± 1.85 | NS | |
9 weeks | 4.04 ± 1.96* | 3.35 ± 1.97* | NS | −2.45 ± 1.45 | −2.99 ± 1.7 | NS | |
12 weeks | 4.81 ± 2.44* | 4.22 ± 2.07* | NS | −1.57 ± 1.21 | −2.12 ± 1.7 | NS | |
Tannerella forsythia | Baseline | 6.56 ± 0.89 | 5.95 ± 1.82 | NS | |||
3 weeks | 1.34 ± 2* | 1.71 ± 2.18* | NS | −5.22 ± 1.72 | −4.57 ± 1.93 | NS | |
6 weeks | 2.96 ± 2.38* | 3.56 ± 2.13* | NS | −3.6 ± 2.15 | −2.56 ± 1.45 | NS | |
9 weeks | 4.22 ± 1.99* | 4.02 ± 2.12* | NS | −2.34 ± 1.81 | −2.07 ± 1.39 | NS | |
12 weeks | 5.24 ± 1.17* | 4.96 ± 1.78* | NS | −1.33 ± 0.94 | −1.06 ± 0.81 | NS | |
Total load | Baseline | 10.11 ± 0.86 | 9.9 ± 0.52 | NS | |||
3 weeks | 7.34 ± 1.22* | 6.93 ± 1.54* | NS | −2.78 ± 0.92 | −2.97 ± 1.66 | NS | |
6 weeks | 7.76 ± 1.01* | 8.04 ± 1.06* | NS | −2.36 ± 0.77 | −1.86 ± 1.03 | NS | |
9 weeks | 8.42 ± 1.19* | 8.24 ± 0.98* | NS | −1.69 ± 1.07 | −1.66 ± 1.02 | NS | |
12 weeks | 8.99 ± 0.99* | 8.49 ± 0.82* | NS | −1.12 ± 1.04 | −1.41 ± 0.7 | NS |
Significance of differences between groups: p > 0.1: not significant (NS); p < 0.1 to >0.05: tendency; p < 0.05: significant (bold).
Significantly different from baseline.
SRP, scaling and rootplaning + placebo lozenge; SRP + P, scaling and rootplaning + probiotic lozenge.