Table 6.
Species | Time point | Mean log10 cfu/ml ± SD | Δ mean log10 cfu/ml | ||||
---|---|---|---|---|---|---|---|
SRP | SRP + P | p-value | SRP | SRP +P | p-value | ||
Aggregatibacter actinomycetemcomitans | Baseline | 3.43 ± 2.29 | 3.58 ± 3.32 | NS | |||
3 weeks | 0.62 ± 1.63* | 0.79 ± 2.13* | NS | −3.52 ± 1.27 | −4.64 ± 2.19 | NS | |
6 weeks | 0.63 ± 1.7* | 1.4 ± 2.56* | NS | −3.49 ± 1.36 | −3.62 ± 2.01 | NS | |
9 weeks | 1.04 ± 1.94* | 1.65 ± 2.85* | NS | −2.99 ± 1.2 | −3.21 ± 2.19 | NS | |
12 weeks | 1.21 ± 2.08* | 2.18 ± 2.83* | NS | −2.78 ± 1.4 | −2.32 ± 1.48 | NS | |
Fusobacterium nucleatum | Baseline | 7.12 ± 1.32 | 6.45 ± 1.66 | NS | |||
3 weeks | 1.7 ± 2.49* | 1.14 ± 2.02* | NS | −5.42 ± 2.21 | −5.3 ± 1.6 | NS | |
6 weeks | 3.11 ± 2.69* | 2.99 ± 2.47* | NS | −4.01 ± 2.41 | −3.45 ± 1.42 | NS | |
9 weeks | 4.17 ± 2.62* | 3.82 ± 2.39* | NS | −2.94 ± 2.31 | −2.63 ± 1.19 | NS | |
12 weeks | 5.47 ± 1.71* | 4.48 ± 2.32* | NS | −1.65 ± 1.2 | −1.96 ± 1.19 | NS | |
Porphyromonas gingivalis | Baseline | 6.93 ± 1.61 | 7.17 ± 1.48 | NS | |||
3 weeks | 3.97 ± 1.68* | 3.49 ± 1.58* | NS | −2.97 ± 1.68 | −3.68 ± 1.2 | 0.089 | |
6 weeks | 4.72 ± 1.79* | 4.62 ± 1.22* | NS | −2.21 ± 1.48 | −2.55 ± 1 | NS | |
9 weeks | 5.53 ± 1.9* | 4.9 ± 1.31* | NS | −1.4 ± 0.82 | −2.27 ± 0.84 | 0.009 | |
12 weeks | 6.05 ± 2.04* | 5.06 ± 1.5* | NS | −0.89 ± 0.67 | −2.11 ± 0.84 | 0.000 | |
Prevotella intermedia | Baseline | 7.64 ± 1.56 | 6.77 ± 2.45 | NS | |||
3 weeks | 3.04 ± 2.24* | 2.79 ± 2.19* | NS | −4.6 ± 2.03 | −4.26 ± 1.65 | NS | |
6 weeks | 4.32 ± 2.16* | 3.28 ± 2.28* | NS | −3.32 ± 1.7 | −3.73 ± 1.69 | NS | |
9 weeks | 4.93 ± 2.41* | 4.22 ± 1.91* | NS | −2.71 ± 1.93 | −2.73 ± 1 | NS | |
12 weeks | 6.08 ± 1.54* | 4.85 ± 1.86* | 0.074 | −1.56 ± 1.15 | −2.05 ± 0.81 | 0.085 | |
Tannerella forsythia | Baseline | 7.25 ± 0.68 | 6.89 ± 0.56 | NS | |||
3 weeks | 1.49 ± 2.18* | 2.28 ± 2.38* | NS | −5.76 ± 2.01 | −4.61 ± 2.17 | NS | |
6 weeks | 3.58 ± 2.34* | 4.23 ± 1.94* | NS | −3.67 ± 2.41 | −2.67 ± 1.56 | NS | |
9 weeks | 4.68 ± 2* | 4.61 ± 1.99* | NS | −2.57 ± 1.91 | −2.28 ± 1.67 | NS | |
12 weeks | 5.74 ± 1.25* | 5.42 ± 1.27* | NS | −1.51 ± 1.23 | −1.48 ± 1.07 | NS | |
Total load | Baseline | 10.56 ± 0.74 | 10.92 ± 0.72 | NS | |||
3 weeks | 8 ± 1.91* | 8.8 ± 1.27* | NS | −2.55 ± 1.75 | −2.12 ± 1.21 | NS | |
6 weeks | 9.15 ± 1.09* | 9.07 ± 1.25* | NS | −1.41 ± 0.92 | −1.85 ± 1.04 | NS | |
9 weeks | 9.51 ± 1.11* | 9.67 ± 1.16* | NS | −1.04 ± 0.98 | −1.26 ± 1.01 | NS | |
12 weeks | 9.89 ± 0.84* | 9.96 ± 0.97* | NS | −0.66 ± 0.62 | −0.97 ± 0.89 | NS |
Significance of differences between groups; p > 0.1: not significant (NS); p < 0.1 to > 0.05: tendency; p < 0.05: significant (bold).
Significantly different from baseline.
SRP, scaling and rootplaning + placebo lozenge; SRP + P, scaling and rootplaning + probiotic lozenge.