Table 7.
Species | Time point | Mean log10 cfu/ml ± SD | Δ mean log10 cfu/ml | ||||
---|---|---|---|---|---|---|---|
SRP | SRP + P | p-value | SRP | SRP + P | p-value | ||
Aggregatibacter actinomycetemcomitans | Baseline | 3.07 ± 2.06 | 3.02 ± 2.86 | NS | |||
3 weeks | 0.68 ± 1.8* | 0.66 ± 1.82* | NS | −2.99 ± 0.78 | −3.93 ± 1.91 | NS | |
6 weeks | 0.75 ± 2* | 1.07 ± 2.27* | NS | −2.9 ± 0.95 | −3.26 ± 1.95 | NS | |
9 weeks | 1.07 ± 2.3* | 1.17 ± 2.46* | NS | −2.51 ± 1.24 | −3.09 ± 2.11 | NS | |
12 weeks | 1.31 ± 2.45* | 1.67 ± 2.66* | NS | −2.2 ± 1.54 | −2.25 ± 1.6 | NS | |
Fusobacterium nucleatum | Baseline | 6.8 ± 1.03 | 5.86 ± 2.17 | NS | |||
3 weeks | 1.34 ± 2.46* | 0.51 ± 1.29* | NS | −5.46 ± 2.11 | −5.35 ± 2.2 | NS | |
6 weeks | 3.2 ± 2.71* | 3.2 ± 2.6* | NS | −3.6 ± 2.44 | −2.65 ± 1.64 | NS | |
9 weeks | 4.32 ± 2.6* | 3.64 ± 2.75* | NS | −2.48 ± 2.29 | −2.22 ± 1.66 | NS | |
12 weeks | 5.82 ± 1.34* | 4.83 ± 2.47* | NS | −0.98 ± 0.83 | −1.02 ± 1.19 | NS | |
Porphyromonas gingivalis | Baseline | 6.7 ± 1.72 | 6.92 ± 1.33 | NS | |||
3 weeks | 3.9 ± 2.02* | 2.94 ± 2.11* | NS | −2.8 ± 2.21 | −3.99 ± 2.28 | 0.093 | |
6 weeks | 4.88 ± 1.77* | 4.42 ± 1.51* | NS | −1.82 ± 1.64 | −2.5 ± 1.31 | 0.071 | |
9 weeks | 5.73 ± 1.98* | 5.23 ± 1.01* | 0.085 | −0.96 ± 0.85 | −1.69 ± 0.94 | 0.011 | |
12 weeks | 6.48 ± 1.61* | 5.75 ± 0.96* | 0.098 | −0.22 ± 0.21 | −1.17 ± 0.76 | 0.000 | |
Prevotella intermedia | Baseline | 7.57 ± 1.13 | 6.74 ± 1.49 | NS | |||
3 weeks | 2.06 ± 2.41* | 2.09 ± 2.28* | NS | −5.51 ± 2.4 | −4.65 ± 2.22 | NS | |
6 weeks | 4.73 ± 1.76* | 3.6 ± 2.14* | NS | −2.84 ± 2.04 | −3.14 ± 1.71 | NS | |
9 weeks | 5.59 ± 1.34* | 4.06 ± 2.38* | 0.085 | −1.98 ± 1.61 | −2.68 ± 1.89 | NS | |
12 weeks | 6.7 ± 1.27* | 5.37 ± 1.34* | 0.017 | −0.87 ± 0.92 | −1.37 ± 0.89 | NS | |
Tannerella forsythia | Baseline | 6.7 ± 0.55 | 6 ± 1.84 | NS | |||
3 weeks | 1.26 ± 1.99* | 1.75 ± 2.27* | NS | −5.44 ± 1.97 | −4.56 ± 2.07 | NS | |
6 weeks | 3.5 ± 2.47* | 3.98 ± 2.11* | NS | −3.2 ± 2.4 | −2.17 ± 1.27 | NS | |
9 weeks | 4.92 ± 2.06* | 4.59 ± 2.25* | NS | −1.78 ± 1.79 | −1.52 ± 1.35 | NS | |
12 weeks | 6.11 ± 1.08* | 5.36 ± 1.82* | NS | −0.59 ± 0.73 | −0.69 ± 0.67 | NS | |
Total load | Baseline | 10.82 ± 0.5 | 10.3 ± 0.35 | NS | |||
3 weeks | 7.76 ± 1.38* | 7.5 ± 1.37* | NS | −3.06 ± 1.35 | −2.8 ± 1.47 | NS | |
6 weeks | 9.18 ± 0.97* | 8.7 ± 1.02* | NS | −1.64 ± 0.9 | −1.6 ± 1.01 | NS | |
9 weeks | 9.76 ± 0.93* | 9.21 ± 0.91* | NS | −1.06 ± 0.85 | −1.1 ± 0.87 | NS | |
12 weeks | 10.31 ± 0.77* | 9.74 ± 0.65* | 0.074 | −0.51 ± 0.55 | −0.56 ± 0.5 | NS |
Significance of differences between groups: p > 0.1: not significant (NS); p < 0.1 to > 0.05: tendency; p < 0.05: significant (bold).
Significantly different from baseline.
SRP, scaling and rootplaning + placebo lozenge; SRP + P, scaling and rootplaning + probiotic lozenge.