Table 3.

Microarray data for the 10 Mycobacterium tuberculosis genes most highly up- and down-regulated upon Rv1747 deletion

Rv number	Gene name	Gene product	Fold regulated	P-value
Rv0005	gyrB	DNA gyrase subunit B	2.0 up	0.001
Rv0046c	ino1	Myo-inositol-1-phosphate synthase Ino1	2.0 up	3.00E−04
Rv0047c	Rv0047c	Conserved hypothetical protein	2.2 up	4.10E−05
Rv0341	iniB	Isoniazid-inducible gene protein IniB	3.8 up	2.40E−04
Rv0342	iniA	Isoniazid-inducible gene protein IniA	3.2 up	8.10E−05
Rv0822c	Rv0822c	Conserved hypothetical protein	2.0 up	4.00E−05
Rv1040c	PE8	PE family protein	2.1 down	0.013
Rv1380	pyrB	Probable aspartate carbamoyltransferase PyrB	2.2 down	0.001
Rv1382	Rv1382	Probable export or membrane protein	2.2 down	6.20E−04
Rv1747	Rv1747	Probable ABC transporter	29.2 down	8.90E−06
Rv1999c	Rv1999c	Probable conserved integral membrane protein	2.2 down	0.004
Rv2007c	fdxA	Probable ferredoxin FdxA	2.1 up	0.005
Rv2265	Rv2265	Possible conserved integral membrane protein	2.1 down	0.005
Rv2396	PE_PGRS41	PE-PGRS family protein	2.0 up	7.00E−04
Rv2415c	Rv2415c	Conserved hypothetical protein	2.3 down	7.90E−04
Rv2528c	mrr	Probable restriction system protein Mrr	2.1 down	1.90E−04
Rv2577	Rv2577	Conserved hypothetical protein	2.1 down	0.015
Rv2814c	Rv2814c	Probable transposase	2.2 down	0.011
Rv3140	fadE23	Probable acyl-CoA dehydrogenase FadE23	2.1 up	0.001
Rv3854c	ethA	Monooxygenase EthA	2.0 up	0.003