TABLE 4.

Allosteric disulfide bonds with −/+RHHook or −LHHook configurations

Protein	Disulfide cysteines	Configuration (PDB identifier)	References
Plasmin(ogen)	462–541, 512–536	−/+RHHook, −LHHook (4DUR)	(28)
β2-Glycoprotein I	288–326	−/+RHHook (1C1Z)	(39, 40, 52)
Angiotensinogen	18–138	−/+RHHook (2WXW)	(43)
Factor XI	362–482	−/+RHHook (2F83)	(44)
Interleukin receptor subunit γ	183–232	−LHHook (2ERJ, 2B5I)	(46, 54–56)
XRCC1	12–20	−LHHook (3LQC, 3K75)	(47)
Vascular endothelial growth factors C and D	156–165	−LHHook (2X1W)	(49, 50, 52, 53)