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. Author manuscript; available in PMC: 2014 Jan 31.
Published in final edited form as: Biol Chem. 2011 Feb 7;392(4):315–325. doi: 10.1515/BC.2011.045

Figure 3. Effects of peptide orientation and chemistry on ATX3 expression.

Figure 3

19-base PNAs (a–c) or 7-base PNAs (d–f) with 8 lysines or arginines at their N or C-terminus were tested in patient fibroblast cell line GM06151 (CAG 74 mutant repeats/24 wild-type repeats) at increasing concentrations. Representative western blot images are presented. Quantification and a nonlinear fitting curve of ATX3 expression is plotted from multiple experiments. Error bars are SEM.