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Photomicrographs of the substantia nigra after immunohistochemistry for p62 in C9ORF72− brains (A) and C9ORF72+ brains (B, low power, and C, high power) of patients with the clinical diagnosis of amyotrophic lateral sclerosis showing neuronal loss and p62-positive cytoplasmic inclusions (arrow) in the C9ORF72+ brain. Bar = 100 μm (A and B), and 20 μm (C).
