Table 2.

Regions Demonstrating Differential BOLD Responses during acquisition of Passive Avoidance Learning

Region		L/R	BA	x	y	z	F	volume
Diagnosis-by-Phase interaction
Orbital frontal cortex	R	11	23	36	−13	14.4	675
Middle frontal gyrus	L	10	−32	41	25	24.0	3834
Superior frontal gyrus	L	8	−17	46	44	15.5	4863
	L	6	−29	−4	45	15.2	1269
Inferior frontal gyrus	R	46	50	38	11	17.7	3942
	L	44	−59	13	20	14.4	1836
Inferior parietal lobule		L	7	−41	−69	45	16.8	3159
Middle temporal gyrus		R	39	47	−58	10	18.9	2808
	R	21	44	3	−33	21.0	2106
Middle temporal/Angular gyrus		L	39	−50	−54	3	19.4	8289
Caudate	L		−2	16	13	13.3	1458
Cerebellum	L		−4	−50	−25	27.6	7371
Diagnosis-by-Response type interaction
Orbital frontal cortex	R	10	5	64	−8	12.3	162
Middle frontal gyrus	L	8	−44	12	49	13.6	486
Parahippocampal gyrus		R	37	35	−41	−10	11.9	216
Main effect of Diagnosis
Superior frontal gyrus	R	6	11	26	66	17.4	2538
	L	6	−8	1	68	17.3	6183
	R	6	47	2	49	18.5	1701
	R	6	37	14	66	15.8	1269
Medial frontal gyrus	R	8	11	27	43	13.2	1134
Middle frontal gyrus	L	10	−35	47	28	12.3	1350
Inferior frontal gyrus/insula	R	44	44	13	13	12.6	945
Insula	L	13	−41	14	0	14.6	2295
Superior parietal lobule		L	7	−35	−72	45	18.7	5508
Superior temporal gyrus		L	22	−53	−33	4	20.5	7992
Middle temporal gyrus		R	39	44	−64	19	16.5	4482
Lingual gyrus	L	18	−20	−88	−13	14.1	1890
Fusiform gyrus		R	19	32	−81	−20	23.8	13041
Amygdala	R		20	−10	−26	10.7	216
Caudate	L		−8	7	16	16.8	12204
Thalamus/pulvinar	R		5	−30	8	13.9	1026

MNI coordinates of peak activation. Regions and BA areas according to Talairach Daemon Atlas. All regions initially thresholded at p<0.005. Regions >547 mm3 survive whole brain correction for multiple comparisons (p < 0.05).