Skip to main content
. Author manuscript; available in PMC: 2014 Jan 31.
Published in final edited form as: Immunity. 2012 Dec 27;38(1):79–91. doi: 10.1016/j.immuni.2012.12.001

Figure 1. Reporter gene expression profile of macrophage populations in Cx3cr1gfp/+, Cx3cr1cre/+:R26-yfp and Tamoxifen-treated Cx3cr1creER/+:R26-yfp mice.

Figure 1

(A) Schematic of modified Cx3cr1 loci. The Cx3cr1cre and Cx3cr1creER mice were crossed to R26-yfp mice, in which irreversible induction of YFP expression is induced upon Cre recombinase expression and activation, respectively.

(B & C) Flow cytometric analysis of CX3CR1+ (B) and CX3CR1 (C) mononuclear phagocyte populations of Cx3cr1gfp/+, Cx3cr1cre/+:R26-yfp and Cx3cr1creER/+:R26-yfp mice. Cx3cr1creER/+:R26-yfp mice were treated for 4 weeks with Tamoxifen prior to analysis. Results are representative of 6 mice per group.