Table 3.
Secondary Analyses
| Total | Autistic Disorder | Unadjusted | Adjusted a | |||||
|---|---|---|---|---|---|---|---|---|
|
| ||||||||
| n | % | n | % | OR | 95% CI | OR | 95% CI | |
| Fish oil use in week (−4) to 8 b | ||||||||
| No fish oil | 46,314 | 54.4 % | 60 | 0.13 % | 1 (ref) | --- | 1 (ref) | --- |
| Use of fish oil | 38,862 | 45.6 % | 54 | 0.14 % | 1.07 | 0.74 – 1.55 | 1.29 | 0.88 – 1.89 |
|
| ||||||||
| Folic acid use in week 22 c | ||||||||
| No folic acid | 32,064 | 40.4 % | 42 | 0.13 % | 1 (ref) | --- | 1 (ref) | --- |
| 1–399 μg/day | 20,872 | 26.3 % | 26 | 0.12 % | 0.95 | 0.58 – 1.55 | 1.02 | 0.62 – 1.67 |
| ≥ 400 μg/day | 26,467 | 33.3 % | 31 | 0.12 % | 0.89 | 0.56 – 1.42 | 0.96 | 0.60 – 1.55 |
a
Adjusted for year of birth, maternal education level, and parity. For maternal education, missing data was included as a separate category in the logistic regression model.
b
Fish oil includes cod liver oil and omega-3 fatty acid supplements.
c
Analyses includes only responders to the food-frequency questionnaire in week 22 (n=79,403). The food-frequency questionnaire included report of brand names of supplements, enabling exact calculations of the amounts of folic acid ingested per day.