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. Author manuscript; available in PMC: 2014 Jan 31.
Published in final edited form as: J Immunol. 2009 Dec 15;183(12):7799–7809. doi: 10.4049/jimmunol.0900155

FIGURE 2.

FIGURE 2

The addition of CD11b− donor APCs accelerated in vivo donor T cell proliferation in allogeneic BMT. A and B, Percentages of: donor CD4+ T cells (A) and CD8+ T cells (B) according to numbers of cell divisions (CFSE dilution). For B6→B6 syngeneic (Syn) transplants only data from HSCs plus T cells transplant; transplants adding CD11b+ or CD11b− APCs yielded similar results (data not shown). C, Numbers of total and Ki67+ donor CD4+ and CD8+ donor T cells at day 3 in the spleen of B6→B10 transplant recipients. Data are means ± SD from four replicate experiments with three mice per treatment group. D–F, T cell chimerism of blood T cells derived from mature T cells in the graft (D), donor HSC-derived T cells (E), and residual host T cells (F). Data are means (±SD) from four replicate experiments, five mice per group. *, p < 0.05; **, p < 0.01; ***, p < 0.001 comparing T cell chimerism in groups receiving donor APCs with HSC and T cell groups.