TABLE 3.

The Frequency of Grade 3–4 Treatment-Related Toxicities in 36 Patients With Invasive Anal Cancer Expressed as the Worst Toxicity Per Patient^*

Type of Toxicity	HIV Positive (N = 13)	HIV Negative (N = 23)
Neutropenia
Grade 3	2 (15%)	3 (13%)
Thrombocytopenia
Grade 3	1 (8%)	1 (4%)
Anemia
Grade 3	2 (15%)	1 (4%)
Dermatitis
Grade 3	3 (23%)	12 (52%)
Grade 4	0	1 (4%)
Mucositis
Grade 3	0	1 (4%)
Infection
Grade 3	1 (8%)	2 (9%)
Dehydration
Grade 3	2 (15%)	2 (9%)
Diarrhea
Grade 3	2 (15%)	3 (13%)
Nausea
Grade 3	0	1 (4%)
Vomiting
Grade 3	0	1 (4%)
Encephalopathy
Grade 4	1 (8%)	0

^*Toxicity data was not available on 9 patients in the HIV-negative group.