Table 1.
Demographics and IOP Characteristics for Each Study Animal
|
Animal # |
Animal ID |
Sex |
Age, y |
Baseline Mean IOP C/EG, mm Hg |
Post-Laser Mean IOP C/EG, mm Hg |
Post-Laser Peak IOP C/EG, mm Hg |
Cummulative IP Insult-CSLT Onset, mm Hg × Day* |
EG Eye Optic Nerve Axon Loss, %† |
| Y1 | 25357 | M | 2.6 | 10/9 | 9/11 | 13/29 | 309 | −29 |
| Y2 | 25564 | F | 2.3 | 8/8 | 9/13 | 13/28 | 183 | −19 |
| Y3 | 26072 | F | 1.5 | 5/6 | 9/10 | 15/32 | 61 | −15 |
| Y4 | 26161 | F | 1.4 | 6/6 | 8/11 | 12/37 | 17 | −4 |
| O1 | AM76 | F | 21.9 | 9/9 | 11/16 | 19/38 | 80 | −12 |
| O2 | AM89 | M | 21.9 | 11/11 | 14/16 | 20/42 | 94 | 2 |
| O3 | AO23 | F | 20 | 9/9 | 10/18 | 15/38 | 649 | −13 |
| O4 | AP02 | F | 18.6 | 7.3/7.3 | 9/11 | 13/41 | 193 | −23 |
Y, young monkeys; O, old monkeys; C, control eyes; EG, experimental glaucoma eyes.
*
Cumulative IOP difference between the EG eye and normal eye from the onset of laser treatment to CSLT onset.
†
Optic nerve axon loss in the EG eye expressed as percent of its contralateral control eye.