Table 2.

ICCVAM Test Substances and Meta-analysis Data Not Used to Assess BG-1Luc EA and AEA Assays Undergoing ICCVAM Validation—and ICCVAM BG-1Luc Data and MCF-7:WS8 Data for Those Same Test Substances

Data in columns 1–9 as described for Table 1. Light gray highlighted data are for I/N test substances that gave a MCF-7 false negative EA or AEA classification according to I/N meta-analysis data in columns 2 or 6. Black highlighted data with white font are for I/N test substances that gave an MCF-7 false positive according to ICCVAM meta-analyses data in columns 2 or 6. Abbreviations: 2,4,5-T, 2,4,5-trichlorophenoxyacetic acid; MPA, medroxyprogesterone acetate; TPA, 12-O-tetradecanoylphorbol-13-acetate.

^a4-Androstenedione AEA Comprehensive assay did not show a good top plateau and hence an IC50 could not be calculated.