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Baseline and 10ng isoproterenol (Iso) stimulated cardiac hemodynamic functions were recorded in 24 week-old wild-type and V1A-TG mice. (A) Aorta Pressure. (B) LVEDP: LV end-diastolic pressure. *p<0.001 vs WT Systolic, #P<0.001 vs WT Diastolic. (C) +dP/dt and –dP/dt: maximal 1st time derivatives of left ventricular (LV) pressure rise. #P<0.001 vs WT ISO. Tables of median, IQR and P values are included in the Supplemental Section.
