Beneficial effects of myocytes GRK2 lowering are reduced by the LTCC blocker verapamil. Echocardiographic measurements of fractional shortening [FS] (A) and left ventricular end diastolic diameter [EDD] (B) at 42 days post MI or sham operation. Mice were supplemented orally with verapamil starting 14 days post MI until the end of the study period (= 42 days post MI). n=6-8/sham group, n=15-25/MI group without verapamil, n=10-13/MI group with verapamil, one-way ANOVA. C, cardiac myocyte BNP mRNA levels 42 days post MI or sham operation; n=5-6/group for sham, n=8-9/group for MI; one-way ANOVA and unpaired two-tailed t-test.