Table 2.

Activity of ceftazidime–avibactam and comparators against select Gram-negative strict anaerobic bacteria27,32,38

Organism	Ceftazidime–avibactam		Ceftazidime		Ceftriaxone
	MIC50/90	MIC range	MIC50/90	MIC range	MIC50/90	MIC range
Bacteroides fragilis	4/32	≤0.06–>64	0.5/>32	0.5–>128	16/128	N/A
Other B. fragilis complex	32/>128	4–>128	>128/>128	8–>128	>64/>64	N/A
Prevotella/Porphyromonas spp.	2/4	≤0.125–8	32/>128	0.5–>128	N/A	N/A
Fusobacterium spp.	N/A	≤0.06–2	N/A	0.125–32	N/A	N/A

Note: MICs were measured in μg/mL.

Abbreviations: MIC, minimum inhibitory concentration; MIC₅₀, MIC that inhibits 50% of isolates; MIC₉₀, MIC that inhibits 90% of isolates; N/A, not available.