The esophagus from mice belonging to three different groups (no OVA; OVA+ diluent; OVA+ allosamidin)(n=12 mice/group) were processed to detect features of esophageal remodeling including, the area of esophageal trichrome staining (Fig 2A), the amount of esophageal collagen (Fig 2B), the area of esophageal fibronectin staining (Fig 2C), the amount of esophageal fibronectin quantitated by Elisa (Fig 2D), and the thickness of the esophageal epithelial basal zone layer (Fig 2E), and the number of esophageal TGFβ1 positive cells (Fig 2F).