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. 2014 Jan 24;9:695–710. doi: 10.2147/IJN.S55255

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© 2014 Cheng et al. This work is published by Dove Medical Press Limited, and licensed under Creative Commons Attribution – Non Commercial (unported, v3.0) License

The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.

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Inhibition by GA-CTS/5-FU nanoparticles in orthotopic liver transplantation mouse model.

Notes: (A) At 5 days after model establishment, mice were treated with GA-CTS/5-FU, CTS/5-FU, 5-FU, or PBS. Mice were killed 10 days after treatment and tumor tissues were sampled and weighed. Data are presented as mean ± SD (n=10). **P<0.01 compared with control; ^#P<0.05 and ^##P<0.01 compared with the 5-FU group. (B) Pathological section of HE stain in different groups (magnification ×400).

Abbreviations: 5-FU, 5-fluorouracil; CTS, chitosan; GA-CTS, glycyrrhetinic acid-modified chitosan; HE, hematoxylin and eosin; PBS, phosphate buffered saline; SD, standard deviation.