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. 2014 Jan 31;9(1):e85886. doi: 10.1371/journal.pone.0085886

Table 1. Participant clinical features by hallucinations.

Hallucinations No hallucinations p
n 28 83
Age (Y) mean (SD) 73.1 (7.1) 68.6 (7.7) 0.006
Sex (Male) n (%) 13 (46%) 33 (40%) 0.7
Duration of PD (Y) mean (SD) 9.0 (4.2) 7.7 (4.6) 0.15
history of psychosis Yes, n (%) 11 (52%) 19 (24%) 0.02
No, n (%) 10 (48%) 60 (76%)
Initial symptoms Tremor, n (%) 11 (46%) 36 (43%) 1.00
Others, n (%) 13 (54%) 47 (57%)
modified H-Y 4–5, n (%) 14 (50%) 26 (31%) 0.11
1–3, n (%) 14 (50%) 57 (69%)
UPDRS-3 median (IQR) 27 (20–39) 20 (14–26) 0.002
MMSE median (IQR) 26 (24–29) 29 (26–30) 0.004
PPQ-A (sleep disorder) median (IQR) 1 (0–2) 0 (0–1) 0.046
L-Dopa dose (mg/day) mean (SD) 493.8 (184.7) 414.8 (173.9) 0.09
DA agonist (LDED mg/day) median (IQR) 25.1 (0–134) 100 (0–168) 0.06
selegiline (mg/day) median (IQR) 0.0 (0.0–3.8) 0.0 (0.0–5.0) 0.50
amantadine (mg/day) median (range) 0.0 (0.0–50) 0.0 (0.0–0.0) 0.23
plasma CRP (mg/L) median (IQR) 0.8 (0.3–1.8) 0.4 (0.1–0.8) 0.003
white blood cell count mean (SD) 5,568 (1,166) 5,233 (1,419) 0.26
albumin (mg/dL) mean (SD) 4.0 (0.3) 4.1 (0.3) 0.09

Statistical analysis was performed as follows; t-test for age, duration, UPDRS–3, MMSE, Dopa dose, white blood cell count, and albumin. Chi-square test for modified H-Y stage. Mann-Whitney U test for PPQ-A score, DA agonist, selegiline, amantadine and plasma CRP because of non-Gaussian distributions.