Table 3. Maximum toxicity per patient.

	Any Grade (with S-1)	Grade 3–4 (with S-1)
Hematological
Neutropenia	3 (3)	1 (1)
Lymphopenia	2 (1)	0
Anemia	5 (5)	0
Thrombocytopenia	8 (6)	0
Increased aspartate aminotransferase	1 (1)	0
Increased alanine aminotransferase	1 (1)	0
Increased alkaline phosphatase	3 (3)	0
Increased total bilirubin	6 (5)	0
Non-hematological
Fatigue	3 (3)	0
Anorexia	3 (3)	0
Nausea	1 (1)	0
Diarrhea	2 (2)	0
Mucositis	2 (2)	0