Table 5.
Univariable Analyses for Association with Mortality in Patients Without Evidence of Myocardial Infarction by clinical history, EKG, or LGE imaging
Variable | HR | CI | LRχ2 | p Value |
---|---|---|---|---|
Age | 1.06 | 1.03–1.09 | 17.4 | <0.0001 |
Male | 0.69 | 0.40–1.22 | 1.6 | 0.21 |
Duration of AF | 0.99 | 0.99–1.00 | 0.93 | 0.33 |
History of Hypertension | 1.58 | 0.94–2.66 | 2.91 | 0.09 |
History of Prior AF Ablation | 0.76 | 0.39–1.48 | 0.64 | 0.42 |
History of Diabetes Mellitus | 2.65 | 1.49–4.69 | 11.2 | 0.0008 |
History of Obstructive Sleep Apnea | 1.56 | 0.94–2.02 | 2.28 | 0.16 |
History of Valvular Heart Disease | 1.60 | 0.76–3.39 | 1.53 | 0.22 |
History of Heart Failure | 2.02 | 1.19–3.41 | 6.84 | 0.009 |
Beta-blockers | 1.43 | 0.81–2.50 | 1.56 | 0.21 |
Calcium Channel Blockers | 0.60 | 0.30–1.23 | 1.92 | 0.17 |
ACE/ARB Inhibitor | 1.42 | 0.85–2.40 | 1.77 | 0.18 |
Class I Anti-arrhythmic | 0.57 | 0.29–1.10 | 2.80 | 0.09 |
Class III Anti-arrhythmic | 1.03 | 0.61–1.75 | 0.01 | 0.89 |
Diuretic Therapy | 1.23 | 0.65–2.32 | 0.39 | 0.53 |
Statin Use | 1.75 | 1.02–3.03 | 4.05 | 0.04 |
Systolic Blood Pressure | 0.99 | 0.98–1.01 | 0.10 | 0.74 |
Diastolic Blood Pressure | 1.01 | 0.98–1.03 | 0.81 | 0.37 |
Heart Rate | 1.01 | 0.99–1.02 | 2.17 | 0.14 |
Body Mass Index | 1.04 | 0.99–1.10 | 2.60 | 0.11 |
Sinus Rhythm (at presentation) | 0.95 | 0.55–1.63 | 0.04 | 0.85 |
AV Delay | 1.00 | 0.99–1.00 | 0.11 | 0.74 |
QRS Duration | 1.01 | 1.00–1.03 | 4.81 | 0.03 |
QTc Duration | 1.01 | 0.99–1.02 | 3.32 | 0.07 |
Echocardiographic Parameters: | ||||
LV Ejection Fraction | 0.99 | 0.97–1.02 | 0.34 | 0.56 |
Estimated PASP | 1.03 | 0.99–1.06 | 2.51 | 0.11 |
LV Diastolic Dimension | 0.99 | 0.94–1.04 | 0.24 | 0.62 |
Left Atrial Dimension | 1.02 | 0.98–1.06 | 0.84 | 0.36 |
Cardiac Magnetic Resonance Parameters: | ||||
LV EDV | 1.00 | 0.99–1.01 | 0.01 | 0.95 |
LV ESV | 1.00 | 0.99–1.01 | 0.25 | 0.62 |
LV EF | 1.00 | 0.98–1.03 | 0.01 | 0.96 |
LV Mass | 1.00 | 0.99–1.01 | 0.13 | 0.72 |
LV Mass Index | 1.00 | 0.98–1.02 | 0.04 | 0.85 |
RV EDV | 1.00 | 0.99–1.01 | 0.26 | 0.61 |
RV ESV | 1.00 | 0.99–1.01 | 0.26 | 0.61 |
RV EF | 0.98 | 0.95–1.01 | 1.78 | 0.18 |
Left Atrial Dimension | 1.02 | 0.98–1.06 | 0.65 | 0.42 |
Late Gadolinium Enhancement: | ||||
Presence of LGE | 4.21 | 2.18–8.14 | 18.3 | <0.0001 |
Extent of LGE | 1.24 | 1.13–1.35 | 22.4 | <0.0001 |