Table 2. Comorbidities (%).* .
| Types of AF | ||||||
| Permanent | ||||||
| Nonpermanent | All | Controlled AF | Uncontrolled AF | p-value | p-value | |
| N = 5622 | N = 4869 | n = 2262 | n = 2246 | (controlled AF vs. uncontrolled AF) | (nonpermanent vs. permanent) | |
| At least one comorbidity | 71.5 | 84.8 | 85.7 | 83.6 | 0.057 | <0.001 |
| HF, by NYHA class | <0.001 | <0.001 | ||||
| No HF or NYHA I | 68.4 | 50.3 | 53.3 | 46.6 | ||
| HF NYHA II | 21.1 | 29.5 | 29.2 | 29.5 | ||
| HF NYHA III or IV | 10.5 | 20.2 | 17.5 | 24.0 | ||
| Valvular heart disease | 18.7 | 35.8 | 37.3 | 33.7 | 0.011 | <0.001 |
| Coronary artery disease | 30.6 | 34.3 | 34.4 | 34.3 | 0.93 | <0.001 |
| Cerebrovascular disease | 11.1 | 17.6 | 18.2 | 16.6 | 0.17 | <0.001 |
| Peripheral arterial disease | 3.4 | 6.0 | 6.9 | 5.4 | 0.042 | <0.001 |
AF, atrial fibrillation; HF, heart failure; NYHA, New York Heart Association.
*
Data are not complete for all patients: the reported percentage is for the number of patients with data available for each given variable.
Table S4 shows comorbidities of permanent AF patients according to revised definition of control used in the RACE II study, i.e., lenient control (in sinus rhythm or in AF with heart rate [HR] <110 beats per minute [bpm]) or no control (no sinus rhythm and in AF with HR ≥110 bpm).