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. 2014 Jan 24;7:13–23. doi: 10.2147/CEG.S51923

Figure 4.

Figure 4

Treatment with TRC160334 resulted in improvement in end points of dextran sulfate sodium-induced colitis in female BALB/c mice.

Notes: (A) Mean disease activity index score; (B) mean histological score; (C) representative immunoblot showing induction of heatshock protein 70 protein in colon, (V1 and V2 are dextran sulfate sodium treated animals, T1 and T2 are dextran sulfate sodium + TRC160334 treated animals); and (D) mean percent change in body weight. Data represent mean ± standard error of the mean. * denotes P<0.05 versus the dextran sulfate sodium group using analysis of variance followed by Dunnett’s post hoc analysis.

Abbreviations: DAI, disease activity index; DSS, dextran sulfate sodium; HSP70, heatshock protein 70.