Figure 3. A hypothetical model of transcription network in plants centered by DELLAs and BZR1/BES1. DELLAs interact with many different transcription factors, including BZR1, BES1, PIFs, MYC2, JAZs, ALC, SCL3 and EIN3/EIL1, to regulate specific developmental processes. BZR1 and BES1 regulate plant growth and development by directly binding to their target genes or interacting with other transcription regulators such as 14-3-3s, BIM1, MYB30, ELF6 and REF,⁶ etc. Arrows indicate activation and bar-ended lines mean inhibition. Bold lines represent direct protein-protein interactions.