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. 2014 Jan 31;9(1):e87162. doi: 10.1371/journal.pone.0087162

Table 2. Respiratory morbidity of hospitalized RSV bronchiolitis patients and non-hospitalized children at the age of 6 years.

Respiratory morbidityat age 6 HospitalizedRSVbronchiolitispatients Non hospitalized Crude Adjusted* Adjusted**
(n = 159) (n = 549) OR 95% CI p-value OR 95% CI p-value OR 95% CI p-value
Respiratory symptoms
Current wheeze 33/155 (21.3) 42/516 (8.1) 3.0 1.9–5.0 <0.001 3.0 1.9–5.1 <0.001 3.2 1.2–8.1 0.002
Current use of asthmamedication
Inhaled steroids 11/159 (6.9) 25/549 (6.9) 1.6 0.7–3.2 0.235 1.5 0.7–3.2 0.255 3.4 1.0–11.3 0.292
Betamimetics 17/159 (10.7) 46/549 (8.4) 1.3 0.7–2.4 0.368 1.3 0.7–2.3 0.378 2.1 0.8–5.7 0.109
Asthma
Doctor’s diagnosisasthma ever 63/158 (39.9) 58/517 (11.2) 5.2 3.5–8.0 <0.001 5.3 3.4–8.0 <0.001 5.8 2.8–11.8 <0.001
Current asthma*** 34/159 (21.4) 29/549 (5.3) 4.9 2.9–8.3 <0.001 4.8 2.8–8.2 <0.001 3.1 1.3–7.5 0.010

Data are numbers (percentages) unless stated otherwise;

*

Adjusted for sex and age;

**

Adjusted for sex, age, birth weight, birth season, smoke exposure during pregnancy and during life, breastfeeding, daycare, siblings, maternal atopy, ethnicity, year of birth, and maternal educational level;

***

Defined as combination of a history of doctor’s diagnosed asthma plus asthma symptoms or medication use in the last 12 months (beta-mimetics or inhaled corticosteroids).