Table 6. Area Under the Curve Statistics for Progression to Advanced Age-Related Macular Degeneration, Geographic Atrophy and Neovascular Disease at 5 and 10 Years After Baseline.
AUC (SE) | AUC (SE) | AUC (SE) | p-value | p-value | |
0 Gene Model | 6 Gene Model | 9 Gene Model | 6 vs 9 Gene Model | 0 vs 9 Gene Model | |
5 Year | |||||
All advanced AMD | 0.873 (0.009) | 0.883 (0.008) | 0.884 (0.008) | 0.24 | 0.01 |
Geographic Atrophy | 0.886 (0.012) | 0.892 (0.012) | 0.893 (0.012) | 0.64 | 0.12 |
Neovascular Disease | 0.860 (0.012) | 0.875 (0.011) | 0.876 (0.011) | 0.30 | 0.02 |
10 Year | |||||
All advanced AMD | 0.898 (0.007) | 0.910 (0.006) | 0.911 (0.006) | 0.56 | 0.001 |
Geographic Atrophy | 0.914 (0.009) | 0.921 (0.008) | 0.920 (0.008) | 0.90 | 0.02 |
Neovascular Disease | 0.879 (0.009) | 0.896 (0.009) | 0.897(0.009) | 0.43 | 0.001 |
SE = Standard Error.