Figure 4. Regulation of gene expression by ParA and ParB of P. aeruginosa.
(A) The β-galactosidase activity in E. coli DH5Δlac transformants bearing pCM132 derivatives with analyzed promoter regions-lacZ fusions and pGBT30 derivatives [72] expressing ParA, ParB or no protein as a control (vector). (B) Fold changes determined by comparative microarray analysis of P. aeruginosa parA null, parB null versus WT strains (p-value ≤0.05; fold-change ≥2) for chosen genes which promoter regions were analyzed using promoter-lacZ fusions in (A).