Figure 2. Current model of IQD1-regulated cellular processes. IQD1 is hypothesized to function as a scaffold protein that recruits in a Ca²⁺-CaM-dependent manner various cargos to kinesin (KHCs) motor complexes via KLCR1. Proteins such as GSTU26 or as yet unidentified RNAs are putative cargo molecules. Ribonucleoprotein complexes containing IQD1 may be assembled in the cell nucleolus/nucleus, exported and directionally transported along microtubule tracks to specific cellular sites related to plant defense response for local mRNA translation, or via plasmodesmata to adjoining cells. A generalized model may apply to other IQD family members.