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. 2014 Jan 31;9(1):e87363. doi: 10.1371/journal.pone.0087363

Table 2. Comparisons between controls and SSc subsets.

Alleles DPB1*02:01 DPB1*03:01 DPB1*13:01 DPB1*17:01 DPB1*35:01
lcSSc p 0.02 2.6×10−4 0.019 0.38 0.33
OR (95% CI) 0.63 (0.41–0.95) 2.9 (1.54–5.47) 1.89 (1.06–3.34) 0.73 (0.34–1.52) 5.64 (0.77–48.3)
dcSSc p 0.08 7.8×10−5 9.7×10−4 0.024 0.25
OR (95% CI) 0.73 (0.51–1.05) 2.95 (1.63–5.34) 2.22 (1.33–3.7) 0.41 (0.17–0.95) 3.03 (0.31–30.1)
ATA (+) p 0.027 1×10−7 1.3×10−4 0.052 0.05
OR (95% CI) 0.66 (0.44–0.97) 3.93 (2.21–6.99) 2.52 (1.51–4.21) 0.46 (0.19–1.07) 5.11 (0.7–43.8)
ATA (−) p 0.045 0.0026 0.025 0.18 0.073
OR (95% CI 0.7 (.049–0.99) 2.39 (1.33–4.3) 1.78 (1.07–2.97) 0.64 (0.33–1.24) 4.48 (0.75–26.9)
ACA (+) p 0.43 0.0026 0.4 0.13 0.001
OR (95% CI) 0.78 (0.39–1.52) 3.51 (1.34–8.83) 1.5 (0.51–4.12) 0.24 (0.01–1.66) 12.95 (1.28–130)
ACA (−) p 0.013 2.6×10−5 0.00026 0.036 0.076
OR (95% CI 0.68 (0.5–0.92) 2.88 (1.72–4.8) 2.21 (1.43–3.42) 0.52 (0.28–0.97) 4.13 (0.75–22.6)
PF (+) p 0.0095 <10−7 3.3×10−4 0.028 0.13
OR (95% CI) 0.65 (0.46–0.91) 3.86 (2.27–6.6) 2.25 (1.4–3.62) 0.47 (0.22–0.97) 3.64 (0.5–31.14)
PF (−) p 0.52 0.79 0.17 0.7 0.037
OR (95% CI 0.87 (0.55–1.35) 1.14 (0.43–3.02) 1.62 (0.82–3.2) 0.86 (0.38–1.92) 6.22 (0.87–44.5)
*

PF =  pulmonary fibrosis; nominal significance p value <0.05; Bonferroni correction for significance was calculated as p<0.0013.