Table 2. Comparisons between controls and SSc subsets.
Alleles | DPB1*02:01 | DPB1*03:01 | DPB1*13:01 | DPB1*17:01 | DPB1*35:01 | |
lcSSc | p | 0.02 | 2.6×10−4 | 0.019 | 0.38 | 0.33 |
OR (95% CI) | 0.63 (0.41–0.95) | 2.9 (1.54–5.47) | 1.89 (1.06–3.34) | 0.73 (0.34–1.52) | 5.64 (0.77–48.3) | |
dcSSc | p | 0.08 | 7.8×10−5 | 9.7×10−4 | 0.024 | 0.25 |
OR (95% CI) | 0.73 (0.51–1.05) | 2.95 (1.63–5.34) | 2.22 (1.33–3.7) | 0.41 (0.17–0.95) | 3.03 (0.31–30.1) | |
ATA (+) | p | 0.027 | 1×10−7 | 1.3×10−4 | 0.052 | 0.05 |
OR (95% CI) | 0.66 (0.44–0.97) | 3.93 (2.21–6.99) | 2.52 (1.51–4.21) | 0.46 (0.19–1.07) | 5.11 (0.7–43.8) | |
ATA (−) | p | 0.045 | 0.0026 | 0.025 | 0.18 | 0.073 |
OR (95% CI | 0.7 (.049–0.99) | 2.39 (1.33–4.3) | 1.78 (1.07–2.97) | 0.64 (0.33–1.24) | 4.48 (0.75–26.9) | |
ACA (+) | p | 0.43 | 0.0026 | 0.4 | 0.13 | 0.001 |
OR (95% CI) | 0.78 (0.39–1.52) | 3.51 (1.34–8.83) | 1.5 (0.51–4.12) | 0.24 (0.01–1.66) | 12.95 (1.28–130) | |
ACA (−) | p | 0.013 | 2.6×10−5 | 0.00026 | 0.036 | 0.076 |
OR (95% CI | 0.68 (0.5–0.92) | 2.88 (1.72–4.8) | 2.21 (1.43–3.42) | 0.52 (0.28–0.97) | 4.13 (0.75–22.6) | |
PF (+) | p | 0.0095 | <10−7 | 3.3×10−4 | 0.028 | 0.13 |
OR (95% CI) | 0.65 (0.46–0.91) | 3.86 (2.27–6.6) | 2.25 (1.4–3.62) | 0.47 (0.22–0.97) | 3.64 (0.5–31.14) | |
PF (−) | p | 0.52 | 0.79 | 0.17 | 0.7 | 0.037 |
OR (95% CI | 0.87 (0.55–1.35) | 1.14 (0.43–3.02) | 1.62 (0.82–3.2) | 0.86 (0.38–1.92) | 6.22 (0.87–44.5) |
PF = pulmonary fibrosis; nominal significance p value <0.05; Bonferroni correction for significance was calculated as p<0.0013.