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. 2014 Jan 31;9(1):e87363. doi: 10.1371/journal.pone.0087363

Table 3. Differentiation of SSc subsets and clinical outcomes with specific HLA-DPB1 alleles.

Alleles N (%) N (%) p OR (95% CI)
Heterozygous
ACA (+) ACA (−)
DPB1*04 13 (34.2) 36 (15.4) 0.0051 2.86 (1.25–6.49)
DPB1*04:01 9 (23.7) 25 (10.7) 0.025 2.59 (1.01–6.55)
DPB1*04:02 4 (10.5) 11 (4.7) 0.15 2.39 (0.6–8.76)
PF (+) PF (−)
DPB1*03:01 39 (19.6) 5 (6.4) 0.0069 3.56 (1.27–10.73)
Homozygous
ACA (+) ACA (−)
DPB1*05:01 3 (7.9) 54 (23.1) 0.033 0.29 (0.07–1.02)

Notes: DPB1*04 only occurred in heterozygotes, heterozygous DPB1*05:01 did not show any association with SSc subsets.